Understanding Why Prevention Treatments Work Differently in Different People

This funding opportunity supports research into the biological mechanisms that explain why prevention interventions produce varying outcomes across individuals. Applicants should design projects that test experimental preventive interventions or controlled challenges in people who are either disease-free or in early disease stages. The goal is to generate mechanistic evidence in humans that enables more targeted and effective precision prevention strategies tailored to individual biological characteristics. Funding of up to £5 million is available over a five-year period for successful applicants.